P51 - ADRB2 gene polymorphisms of the asthma pediatric patients in Russia’s Perm region
نویسندگان
چکیده
B2 adrenergic receptor (ADRB2) gene variation could explain differences in bronchodilator response among patients with asthma or identify a subgroup of patients with reduced response. The aim of our research was identified polymorphisms in the ADRB2 gene in Russian asthma pediatric patients (in Perm region). 44 children from 3 to 18 years of age with bronchial asthma were examined. Mild asthma was in 95,5%, moderate asthma – in 4,5%. Gly16Arg and Gln27Glu mutations of ADRB2 gene were identified by PCR technique.
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